Phyto-4

Clinically-researched botanicals to support immune, cellular and tissue health* Perluxan® is a clinically studied extract of hops specifically developed to promote joint health. In a randomized, double-blind placebo-controlled trial of 36 subjects, the benefits of Perluxan® on joint comfort reached statistical significance within two hours of the first dose and were sustained over the 14-day period. Perluxan® is free of sleep-inducing and phytoestrogenic compounds typically associated with hops extracts. The alpha and iso-alpha acids in Perluxan® maintain healthy NF-kappa B-associated expression of COX-2 and cytokines such as IL-6 and TNFα in connective tissue. Curcumin complements Perluxan® through its extensively characterized effects on cytokine-mediated signal transduction, matrix metalloproteinase (MMP) expression and multiple components of the arachidonic acid cascade. Curcumin C3 Complex® is the subject of extensive ongoing clinical investigations at numerous hospitals and universities. Ginger promotes joint health through maintaining healthy cytokine signaling in cartilage and the synovium. 5–LOXIN® Boswellia serrata extract provides the highly bioactive triterpenoid AKBA, which supports connective tissue structural composition and comfort through supporting healthy immune responses, 5-lipoxygenase activity, and synovial matrix metalloproteinase 3 (MMP-3) levels. In a 3-month double-blind, placebo-controlled study of 75 subjects, significant functional support and comfort scores were evident as early as day 7.* • Supports immune, cellular and tissue health* • Made with hypoallergenic, vegan ingredients

If pregnant or lactating, consult your physician before taking this product. Rare side effects of boswellia or turmeric include G.I. upset, acid reflux, diarrhea or skin rash. Consult your physician for more information.Ginger and curcumin may be contraindicated with blood thinning medications. Studies suggest boswellia moderates 5-lipoxygenase and therefore may interact with leukotriene inhibitors. Hops may be contra-indicated with CNS depressants. Consult your physician for more information.*These statements have not been evaluated by the Food & Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease.